ANDREW GEALL,DEREK O'HAGAN,LUIS BRITO,MANMOHAN SINGH,MICHELLE CHAN,DEREK OHAGAN
申请号:
BR112014000227
公开号:
BR112014000227A8
申请日:
2012.07.06
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
This invention generally relates to cationic oil-in-water emulsions that can be used to deliver nucleic acid molecules, such as an RNA molecule. The emulsion particles comprise an oil core and a cationic lipid. The emulsion particles have an average diameter of about 80 nm to about 180 nm, and the emulsion have an N/P ratio of at least 1.1:1.