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TECHNETIUM-99M LABELED COMPLEX OF GOLD NANOPARTICLE-GOLD BINDING PEPTIDES, AND METHOD OF MAKING AND USING THE SAME
专利权人:
发明人:
Beom Su Jang,Sang Hyun Park,Joo-Sang Lee,Jong-Kook Rho
申请号:
US14175940
公开号:
US20140314668A1
申请日:
2014.02.07
申请国别(地区):
US
年份:
2014
代理人:
摘要:
There is provided a method for preparing a 99mTc labeled gold nanoparticles-gold binding peptide, including: (a) coating gold nanoparticles with a gold binding peptide and (b) labeling a composed 99mTc tricarbonyl precursor on the gold binding peptide coated on the gold nanoparticles. The 99mTc labeled gold nanoparticles-gold binding peptide prepared by the method according to the present invention is expected to be usefully employed for manufacturing a molecular contrast agent (imaging agent) which is traceable in organisms using imaging apparatuses such as gamma imaging and single photon emission computed tomography due to high labeling yield and good in-vivo stability.
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中国工程科技知识中心
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