ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НАУЧНО-ПРОИЗВОДСТВЕННЫЙ ИННОВАЦИОННЫЙ ВНЕДРЕНЧЕСКИЙ ЦЕНТР";LIMITED LIABILITY COMPANY "SCIENTIFIC-INDUSTRIAL INNOVATION DEPLOYMENT CENTER"
发明人:
BAKLANOV, Anatoly Maximovich,БАКЛАНОВ, Анатолий Максимович,VALIULIN, Sergey Vladimirovich,ВАЛИУЛИН, Сергей Владимирович,ONISCHYK, Andrey Alexandrovich,ОНИЩУК, Андрей Александрович,ABDIEV, Oleg Radzhab
申请号：
EAEA2018/000008
公开号：
WO2019/129339A1
申请日:
2018.12.24
申请国别(地区):
EA
年份:
2019
代理人:
摘要：
The invention relates to methods for producing a medicinal aerosol. The problem of developing an effective method of generating a medication in aerosol form is solved by a method of generating a medication in aerosol form that comprises delivering heated air to a starting material of a medication in the form of a multi-layered tablet, evaporating the starting material of a medication with the subsequent nucleation of the resulting supersaturated steam and the growth of the formed aerosol particles by condensation, and delivering the resulting aerosol into the lungs of a patient. According to the method, the starting material of a medication is in the form of a multi-layered, e.g. three-layered, tablet, the top and bottom layers of which are formed by a medication, and the middle layer of which is comprised of compressed cellulose, the adhesive properties of which allow a medication which is initially in either a solid or a liquid state, or which transitions from a solid into a liquid state as a result of heating, to be retained during the generation of an aerosol. The advantageous effect of the proposed method is achieved in that the starting material of a medication, i.e. the multi-layered tablet, makes it possible to effectively sublimate a broad range of medications in both solid and liquid states, including medications which melt when heated. Advantages: strict dosing of a medication transformed into an aerosol； more effective conversion of the starting material of a medication into an aerosol.L'invention concerne des procédés de production d'aérosol médicamenteux ； l'objectif visé est la mise au point d'un procédé plus efficace de génération de médicaments sous forme d'aérosol qui est réalisé grâce à la génération d'un médicament sous la forme d'un aérosol et comprend l'amenée d'air chauffé sur la substance initiale du médicament sous forme de comprimé multicouches, l'évaporation de la substance initiale du médicament suivi d'une nucléation d'une partie de vape
