Choon Kit Wong;Chueh Loo Poh;Nazanin Saeidi;Matthew Wook Chang
发明人:
Matthew Wook Chang,Chueh Loo Poh,Choon Kit Wong,Nazanin Saeidi
申请号：
US13586657
公开号：
US20130052164A1
申请日:
2012.08.15
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to an isolated nucleic acid molecule comprising a first nucleotide sequence encoding a protein that detects the presence, amount or both of a pathogenic microorganism by forming a complex with a protein produced by said pathogenic microorganism； a second nucleotide sequence encoding an antimicrobial peptide, wherein the antimicrobial peptide is effective against the pathogenic microorganism detected by the protein encoded by the first nucleotide sequence, wherein the second nucleotide sequence is under control of a promoter that is induced by the complex of the protein encoded by the first nucleotide sequence and the protein produced by said pathogenic microorganism. A recombinant microorganism comprising the isolated nucleic acid molecule and a method of sensing and killing pathogenic microorganisms is also described.
