The Board of Trustees of the University of Illinois;Felix ECHEVERRIA;Luisa Fernanda BERRIO
发明人:
Jean Paul ALLAIN,Akshath SHETTY,Luisa Fernanda BERRIO,Felix ECHEVERRIA
申请号:
US16500685
公开号:
US20200208291A1
申请日:
2018.04.06
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are methods for the controlled, independent modification of the surface of magnesium-based materials and compositions generated thereby. The methods allow for the alteration of multiple surface characteristics including generation of precise nanostructures, morphology, crystallography, chemical hybridizations and chemical composition for controlled bioresorption and/or increased biocompatibility, for example, osseointegration, hydroxyapatite formation, osseoconduction, cell adhesion, cell proliferation, enhanced local mechanical properties (elasticity, modulus, surface texture, porosity), hydrophobicity, hydrophilicity, steric hindrance, modulating-immuno response, anti-inflammatory properties and/or anti-bacterial properties.