The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier for the prevention, treatment or alleviation of IgE-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.本發明係關於提供新穎免疫原,其包含抗原性IgE肽,較佳連接於免疫原性載體,用於預防、治療或減輕IgE介導之病症。本發明進一步關於製造此等藥劑之方法,其免疫原性組合物及醫藥組合物,及其於醫學中之用途。