PYRROLIDINE DERIVATIVES

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专利权人:

Hoffmann-La Roche Inc.

发明人:

Henner Knust,Andreas Koblet,Matthias Nettekoven,Hasane Ratni,Claus Riemer,Walter Vifian

申请号：

US13779780

公开号：

US20130184249A1

申请日:

2013.02.28

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention relates to compounds of formulawherein R1, R2, R3, R4, Z, and n are as defined hereinor to a pharmaceutically active salt thereof. Compounds of the invention are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinsons disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/