James J. Yoo;Justin M. Saul;Sittadjody Sivanandane;Anthony Atala;Emmanuel Opara
发明人:
Emmanuel Opara,James J. Yoo,Justin M. Saul,Sittadjody Sivanandane,Anthony Atala
申请号：
US14002504
公开号：
US20140127308A1
申请日:
2012.02.21
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition； in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described.
