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METHOD AND SYSTEM FOR ELECTRONIC MDI MODEL
专利权人:
CHIESI FARMACEUTICI S.P.A.
发明人:
David Andrew Lewis
申请号:
US14359181
公开号:
US20140305429A1
申请日:
2012.12.03
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A method and system for optimizing the dispensing of aerosol medicaments by “pulsing” a total dose volume as a series of shorter, low volume bursts is described. Aerosol performance when metering at a low volume e.g. <;10 μL is enhanced by an increase in the fine particle fraction, particularly when pulsing a dose to achieve a high total dose volume. By utilising a solenoid valve, the system can deliver a medicament in a single low volume pulse; or in multiple low volume pulses. Performance can be tailored to obtain a preferred fine particle dose and fraction. By manipulating the solenoid valve timings, a single formulation with a concentration X may be used to provide a range of doses. A minimum interval between pulses to achieve separate “non-interacting” plumes which allow keeping total inhalation time comparable to a conventional single dose MDI actuation is also described.
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中国工程科技知识中心
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