#$%^&*AU2013201510A120130404.pdf#####ABSTRACT The present invention relates to bioactive ingredients that include isolated bioactive fractions derived from cell juice of fresh biomass of a feverfew (Tanacetum s partheniuni) plant. The bioactive fractions are either free of or substantially free of aunsaturated y-lactones (e.g., parthenolide). Further, the bioactive fractions have antiinflammatory and antioxidant activity. The present invention also relates to a method for isolating a bioactive fraction that is derived from cell juice of fresh biomass of a feverfew (Tanacetum partheniuni) plant and that is at least substantially free of x10 unsaturated y-lactones (e.g., parthenolide). The present invention also relates to a method for preparing a stabilized cell juice serum fraction and a stabilized concentrated cell juice serum fraction that are free of c-unsaturated y-lactones (e.g., parthenolide). The present invention also relates to a bioactive composition that includes a mixture of one or more of the isolated bioactive fractions of the present invention. 41413651 (GHMatters) P78726.AU.1 7/03/13