Torsten Dreier,Christophe Frederic Jerome Blanchetot,Johannes Joseph Wilhelmus De Haard
申请号：
US13205327
公开号：
US08524231B2
申请日:
2011.08.08
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention relates to a platform technology for production of antigen binding polypeptides having specificity for a desired target antigen which is based on the conventional antibody repertoire of species in the family Camelidae, and to antigen binding polypeptides obtained using this technology platform. In particular, the invention provides an antigen binding polypeptide comprising a VH domain and a VL domain, wherein at least one hypervariable loop or complementarity determining region (CDR) in the VH domain or the VL domain is obtained from a VH or VL domain of a species in the family Camelidae.
