It refers to combinations comprising timolol and a compound useful for the treatment of rosacea selected from ivermectin, metronidazole and praziquantel and the use of these combinations in the topical treatment of rosacea. Claim 1: Combination for topical use comprising (a) timolol or a pharmaceutically acceptable salt thereof, and (b) an active compound useful for the treatment of rosacea selected from ivermectin, metronidazole, praziquantel and pharmaceutically acceptable salts thereof. Claim 7: Pharmaceutical composition suitable for topical administration comprising a combination according to any one of claims 1 to 5,(a) And (b) ingredient appear in the same expression； claim 9: pharmaceutical ingredient, according to any one of the requirements of any item 7 or 8, the ingredient is an emulsion, cream or gel. Claim 14: method of treating patients with headache, including pathological combination of patients according to any one of 1 to 5, or pathological combination of drug ingredients according to any one of 7 to 10. 11. Claim 17: use of (a) timolol or far salt1. In the production of a drug prepared with (b) anti-inflammatory agent and (b) anti-inflammatory agent for staining, any one or two claims shall be considered as acceptable；3, 4, 5Refiere a combinaciones que comprenden timolol y un compuesto útil para el tratamiento de rosácea seleccionado de ivermectina, metronidazol y praziquantel y al uso de estas combinaciones en el tratamiento tópico de rosácea. Reivindicación 1: Combinación para su uso tópico que comprende (a) timolol o una sal farmacéuticamente aceptable del mismo, y (b) un compuesto activo útil para el tratamiento de rosácea seleccionado de ivermectina, metronidazol, praziquantel y sales farmacéuticamente aceptables de los mismos. Reivindicación 7: Composición farmacéutica adecuada para administración tópica que comprende una combinación según una cualquiera de las reivindicaciones 1 a 5, en la que los componentes (a) y (b) están presentes en l
