The present invention relates to a multilayered miniparticle for oral use comprising, from the inside to outside:A) a core of an active substance；B) an inner film layer which is protective or for the modified release；C) a layer of at least an active substance which is equal to or different from the one in the core A)；D) an outer film layer which more rapidly releases compared to the inner film layer which is protective or for the modified release B).The invention relates to a method for a multilayered miniparticle preparation too and formulations for oral use comprising multilayered miniparticles according to the present invention.
