An injection syringe device includes a tubular barrel, a plunger, and a piezo-chromic pressure indicator. The plunger has a distal tip and is designed to fit tightly and to reciprocate within the tubular barrel. Pulling the plunger out of the tubular barrel draws a liquid or a gas inside the tubular barrel in a space between the distal tip and a distal end of the tubular barrel and pushing the plunger into the tubular barrel expels the liquid or gas from the space. The piezo-chromic pressure indicator changes color to indicate pressure applied on the liquid or gas being expelled and/or target tissue being injected with the liquid or gas.
