DERIVE DE SACCHARIDE D'UNE CHARGE UTILE TOXIQUE ET CONJUGUES D'ANTICORPS DE CELUI-CI

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专利权人:

GLYKOS FINLAND OY

发明人:

HELIN, JARI,SAARINEN, JUHANI,SATOMAA, TERO,EKHOLM, FILIP S.

申请号：

CA2954934

公开号：

CA2954934A1

申请日:

2015.06.26

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

A molecule comprising a saccharide bound via an O- glycosidic bond to a hydroxyl group of a toxic payload molecule is disclosed. An antibody-drug conjugate comprising an antibody covalently bound to a toxic payload molecule, optionally via a linker group,and a saccharide bound via an O- glycosidic bond to a hydroxyl group of the toxic payload molecule is further disclosed.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/