The Brigham and Women's Hospital; Inc.;The Brigham and Womens Hospital
发明人:
Blumberg, Richard S.,Huang, Yu-Hwa
申请号:
AU2013329083
公开号:
AU2013329083B2
申请日:
2013.10.11
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The technology described herein relates to compositions and methods for enhancing the immune response and/or reducing T cell tolerance in a subject. In some embodiments, the technology described herein relates to administering inhibitors of two or more of CEACAM1, PD1, and/or LAP to, e.g., synergistically reduce T cell tolerance.