Disclosed is a skin whitening composition using an extract of Limonium tetragonum, which shows the melanin production inhibitory activity in a concentration-dependent manner when being treated on melanoma cell line B16F10 cells of mice stimulated by &alpha-MSH, which is a melanin production inducer. The extract of Limonium tetragonum is obtained by using water, ethanol, or a mixed solvent thereof. The skin whitening composition of the present invention can be commercialized into foods, cosmetics, medicines, etc., and can have relatively less side effects compared to synthetic skin whitening agents since Limonium tetragonum roots have been used for edible purposes.COPYRIGHT KIPO 2017본 발명은 멜라닌 생성 유도제인α-MSH로 자극된 마우스 흑색종 세포주인 B16F10 세포에 처리될 때 농도 의존적으로 멜라닌 생성 억제 활성을 보이는 갯질경 추출물을 이용한 피부 미백용 조성물을 개시한다.
