A catheter procedure system including a user interface for receiving at least a first user input and a second user input and a guide catheter is provided. The catheter procedure system also includes a guide catheter actuating mechanism coupled to the guide catheter and a Y-connector. The guide catheter actuating mechanism is configured to advance and retract the guide catheter in response to the first user input and to rotate the guide catheter in response to the second user input. The catheter procedure system includes a first connector coupling the Y-connector to the guide catheter actuating mechanism, and the first connector is configured to allow the Y-connector to advance and retract with the guide catheter and to allow the guide catheter to rotate without also causing the Y-connector to rotate.
