ASTRAZENECA AB;BERNARD CHRISTOPHE BARLAAM;LAURENT FRANCOIS ANDRE HENNEQUIN;ROBERT HUGH BRADBURY
发明人:
BERNARD CHRISTOPHE BARLAAM,LAURENT FRANCOIS ANDRE HENNEQUIN,ROBERT HUGH BRADBURY
申请号:
IL17428406
公开号:
IL174284A
申请日:
2006.03.13
申请国别(地区):
IL
年份:
2014
代理人:
摘要:
The invention concerns quinazoline derivatives of Formula (I): wherein each of R1, X1, R2, R3, R5, n and m have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumors which are sensitive to inhibition of EGF and erbB receptor tyrosine kinases.