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Nucleic acid encoding a self-assembling split-fluorescent protein system
专利权人:
发明人:
Geoffrey S. Waldo,Stephanie Cabantous
申请号:
US14166770
公开号:
US09081014B2
申请日:
2014.01.28
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention provides a protein labeling and detection system based on self-complementing fragments of fluorescent and chromophoric proteins. The system of the invention is exemplified with various combinations of self-complementing fragments derived from Aequorea victoria Green Fluorescent Protein (GFP), which are used to detect and quantify protein solubility in multiple assay formats, both in vitro and in vivo.
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