James C. Samuelson,Carine Robichon-Iyer,Jianying Luo
申请号:
US13821113
公开号:
US08981067B2
申请日:
2011.08.26
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Compositions relating to a combination of two types of separation matrix and to variant host cells which contain at least one essential host protein that is fused to an affinity binding tag or has been mutated to replace at least two of a plurality of histidines or basic amino acids are provided. Methods are also provided that relate to isolating a recombinant protein from a lysate.