Oral administration of Vaccines, based on transgenic microalgae that encode an Antigen encoded in a Subcellular compartment; methods that include such a vaccine.
Comprising an Edible Vaccine transgenic eukaryotic microalga, comprising AN EXPRESSION cassette comprising a polynucleotide encoding a exogenous antigen, where the Exogenous Antigen is encoded in a Subcellular compartment of the cell of the alga. Methods oral delivery of an Antigen comprising the Administration of a transgenic eukaryotic microalgae.Vacunas comestibles en base a microalgas transgénicas que comprenden un casete de expresión que codifica un antígeno exógeno expresado en la vacuola de la microalga.