The present invention provides a topical composition for application to a keratinous tissue comprising a cosmetically or pharmaceutically acceptable carrier one or more selected from potassium, zinc, calcium, rubidium disposed in the cosmetically or pharmaceutically acceptable carrier and one or more peptides disposed in the cosmetically or pharmaceutically acceptable carrier.本發明提供一種施用至角質組織之局部用組合物,其包含化妝品或醫藥學上可接受之載劑;一或多種選自鉀、鋅、鈣、銣之物質置於該化妝品或醫藥學上可接受之載劑中;及一或多種肽置於該化妝品或醫藥學上可接受之載劑中。
