OMOTO, Kiyoyuki,OWEN, Robert McKenzie,PRYDE, David Cameron,WATSON, Christine Anne Louise,TAKEUCHI, Mifune
申请号:
LT13812165
公开号:
LT2938615T
申请日:
2013.12.04
申请国别(地区):
LT
年份:
2016
代理人:
摘要:
The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain.