SWAIN, NIGEL ALAN,BROWN, ALAN DANIEL,JONES, LYN HOWARD,MARRON, BRIAN EDWARD,RAWSON, DAVID JAMES,RYCKMANS, THOMAS,STORER, ROBERT IAN,WEST, CHRISTOPHER WILLIAM
申请号:
CA2950393
公开号:
CA2950393A1
申请日:
2015.05.29
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I), or a pharmaceutically acceptable salt thereof, wherein X, R1, R2, R3a, R3b and R4 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.