INHIBITORS OF SERIN PROTEASE, IN PARTICULAR HEPATITIS C-VIRUS NS3 NS4A PROTEASE, WITH A CONDENSED RING SYSTEM

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专利权人:

VERTEX PHARMACEUTICALS INCORPORATED;PERNIE, ROBERT B.;PITLIK, JANOS;VAN DRIE, JOHN H.

发明人:

PERNI, ROBERT,PITLIK, JANOS,VAN DRIE, JOHN,FARMER, LUC

申请号：

AT02782236

公开号：

AT539744T

申请日:

2002.10.24

申请国别(地区):

AT

年份:

2012

代理人:

摘要：

The present invention relates to peptidomimetic compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/