Methods and apparatus for monitoring fatigue and notifying an individual are described. The individual may be an operator of a vehicle, equipment, or machine, a student, or other person that may experience fatigue. Motion of the individual is monitored to detect a predescribed motion in response to a stimulus to first determine a base responsiveness profile. Afterwards, a current responsiveness profile is determined based on a prescribed motion in response to a stimulus, and if the current responsiveness profile exceeds a predetermined threshold of the base responsiveness profile, a notification is issued to the individual and, optionally, another person such as an employer, teacher, or parent.