The present invention relates to a syringe comprising an injection syringe body (1) and a syringe handle (4), configured to cooperate with one another in order to ensure a locking function between the injection syringe body (1) and the syringe handle (4). The injection syringe body (1) comprises a longitudinal hub (2) comprising at least one female or male retaining means (26), and a protective sheath moveable along said longitudinal hub (2) and able to cover in a retracted position the at least one retaining means (26) of the longitudinal hub (2). The syringe handle (4) comprises at least one male or female retaining means (8) intended to cooperate with the at least one female or male retaining means (26) of the longitudinal hub (2), ensuring a retaining function, said cooperation being named locking position. The syringe further comprises at least one blocker (7), said at least one blocker (7) ensuring a radial holding function when the retracted and the locking positions are both engaged.
