FEDERALNOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "TSENTRALNYJ NAUCHNO-ISSLEDOVATELSKIJ INSTITUT TRAVMATOLOGII I ORTOPEDII IMENI N.N. PRIOROVA" MINISTERSTVA ZDRAVOOKHRANENIJA ROSSIJSKOJ FEDERATSII
发明人:
URAZGILDEEV RASHID ZAGIDULLOVICH,Уразгильдеев Рашид Загидуллович,KESJAN GURGEN ABAVENOVICH,Кесян Гурген Абавенович,BERCHENKO GENNADIJ NIKOLAEVICH,Берченко Геннадий Николаевич,ARSENEV IGOR GENNADEVICH
申请号：
RU2012127718/14
公开号：
RU0002508062C1
申请日:
2012.07.23
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to traumatology and orthopedics, and can be used for prevention of purulent-inflammatory complications from application of apparatuses of external fixation in the process of treatment of patients in traumatology and orthopedics. For this purpose transosseous osteosynthesis of long tubular bones is performed by introduction of wires and intraosseous rods of compression-distraction apparatus of external fixation into their proximal and distal fragments. Antimicrobial substance is applied on the surface of wires and intraosseous rods before their introduction into proximal and distal fragments, as well as on degreased surface of patients skin in places of entrance and exit of wires and intraosseous rods. As antimicrobial means used is gel-like nanostructured composite implant. It is replaced on degreased surface of skin in places of entrance and exit of wires and intraosseous rods 2-4 weeks after initial application. Composite implant includes platelet-enriched autoplasma, mixed in ratio 1:1.0-2.0 with granules of complex alloplastic preparation on the basis of hydroxyapatite, which contains 50-60 wt % of collagen. Said complex alloplastic preparation additionally contains 0.08-2.8 wt % of colloid solution of zerovalent metal silver Ag0, or gold Au0, or copper Cu0, or palladium Pd0, or platinum Pt0, which is introduced into its granules at preparation stage. Size of introduced colloid zerovalent metal nanoparticles constitutes from 2 nm to 40 nm.EFFECT: method ensures efficient prevention of purulent-inflammatory complications in such patients due to elimination of microbial risk of bacterial contaminations in treatment of patients by means of apparatuses of external fixation.5 cl, 5 exИзобретение относится к медицине, а именно к травматологии и ортопедии, и может быть использовано для профилактики гнойно-воспалительных осложнений при использовании аппаратов внешней фиксации в процессе лечения пациентов в
