Therapeutic DLL4 binding proteins

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专利权人:

AbbVie Inc.

发明人:

Li, Yingchun,Gu, Jijie James,Morgan-Lappe, Susan,Chen, Mingjiu,Hsieh, Chung-Ming

申请号：

AU2015202980

公开号：

AU2015202980A1

申请日:

2015.06.04

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

#$%^&*AU2015202980A120150625.pdf#####THERAPEUTIC DLL4 BINDING PROTEINS ABSTRACT DLL4 binding proteins are described herein, including antibodies, CDR-grafted antibodies, humanized antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 and/or VEGF activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis.

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中国工程科技知识中心

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http://www.ckcest.cn/home/