isolated polynucleotide, substantially purified polypeptide, vector, host cell, recombinant reapply competent retrovirus, and methods for treating an individual with a proliferative cell disorder, and for treating a proliferative cell disorder in an individual
CHRISTOPHER R. LOGG,DOUGLAS JOLLY,HARRY E. GRUBER,OMAR D. PEREZ
申请号：
BRPI0919113
公开号：
BRPI0919113A2
申请日:
2009.09.26
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
This disclosure provides modified cytosine deaminases (CDs). The disclosure further relates to cells and vector expressing or comprising such modified CDs and methods of using such modified CDs in the treatment of disease and disorders.
