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CHIMERIC ANTIGEN RECEPTOR THAT BINDS HLA-DR AND CAR-T CELL
专利权人:
Ltd.;Eutilex Co.
发明人:
Byoung S. Kwon,Young Ho Kim,Kwang Hee Kim,Ji Won Chung,Young Gyoon Chang,Bo Rim Yi,Jung Yun Lee,Seung Hyun Lee,Sun Woo Im,Jin Kyung Choi,Hyun Tae Son,Eun Hye Yoo
申请号:
US16715462
公开号:
US20200237821A1
申请日:
2019.12.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to an antigen-binding molecule comprising a heavy chain variable region comprising a heavy-chain complementarity-determining region 1 (HCDR1) comprising an amino acid sequence represented by Sequence No. 1, an HCDR2 comprising an amino acid sequence represented by Sequence No. 2, and an HCDR3 comprising an amino acid sequence represented by Sequence No. 3; a light-chain variable region comprising a light-chain complementarity-determining region 1 (LCDR1) comprising an amino acid sequence represented by Sequence No. 4, an LCDR2 comprising an amino acid sequence represented by Sequence No. 5, and an LCDR3 comprising an amino acid sequence represented by Sequence No. 6; wherein the antigen-binding molecule is a T cell receptor (TCR); and to a cell line expressing the same.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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