Devices and systems are provided for the remote monitoring of physiological parameters of a patient. An exemplary wireless physiological monitoring device comprises a substrate formed of a flexible biocompatible material. The substrate has a surface for affixing to the skin of a patient. A wireless data transmission device, a biosensor, and a power source are integrated with the substrate. The biosensor is configured to measure a physiological parameter. Flexible conductors are integrated with the substrate and are configured to electrically couple the biosensor and the power source with the data transmission device.