FUMITAKA KAMACHI,NAOKO OHTANI,SHINICHI KOIZUMI,TAKAKO OKUMURA,TZE MUN LOO
申请号：
BR112018007947
公开号：
BR112018007947A2
申请日:
2017.11.02
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
This invention is directed to prostaglandin E2 receptor 4 (EP4) antagonists useful in the treatment of nonalcoholic steatohepatitis (NASH)-associated liver cancer in a human or animal. The method comprises administering one or more of Compound A, Compound B or Compound C, or pharmaceutically acceptable salts thereof, as the EP4 antagonist(s). The method may include a pharmaceutical composition comprising the EP4 antagonist, and may include one or more other active agents and/or therapies.
