Shyam B. Karki,Peter Zawaneh,Cheuk-Yui Leung,Kalyan Vasudevan,Yiqing Lin,Jin Xu,Andrea Trementozzi
申请号：
US15527531
公开号：
US20180153845A1
申请日:
2015.11.19
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides novel pharmaceutical compositions of dimethyl fumarate. The pharmaceutical compositions of the present invention are in the form of a bead and comprise (i) an inert core； (ii) a first layer surrounding the inert core, wherein the first layer comprises dimethyl fumarate； and (iii) an enteric coating surrounding the first layer. Also provided are pharmaceutical compositions in the form of a bead comprising a core and an enteric coating surrounding the core, wherein the core comprises dimethyl fumarate. Methods of using the pharmaceutical compositions of the present invention for treating multiple sclerosis are also included.
