John Sigurd Svendsen,Øystein Rekdal,Baldur Sveinbjørnsson,Lars Vorland
申请号:
US12217160
公开号:
US08143211B2
申请日:
2008.07.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides a cytotoxic 7 to 25-mer peptide with three or more cationic residues which has one or more non-generic bulky and lipophilic amino acids, as well as esters, amides, salts and cyclic derivatives thereof as well as methods of preparing the peptides, pharmaceutical compositions containing them, and their use as medicaments, particularly as antibacterial or antitumor agents.