The invention relates to a compression system (1) for compression against a puncture site of a vessel in a patient, comprising: a compression element (4) adapted to apply a pressure against said puncture site a tightening unit (5) adapted to extend around a part of or the whole of the patients body to fixate and to tighten the compression element against said puncture site wherein the compression element is provided with a placement mark (18, 19, 22, 23, 24, 25) indicating where the compression element should be placed in relation to an entrance site through the skin of the patient made to reach said puncture site, in order to apply pressure against said puncture site.