Gary Piazza,Xi Chen,Herbert Weissbach,Shailaja Kesraju Allani
申请号:
US16495013
公开号:
US20200095184A1
申请日:
2018.03.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The disclosure provides chemical compounds possessing therapeutic and/or protective properties against oxidative damage. Methods of making such therapeutic and/or protective compounds and associated compositions are also provided, as are methods for their use, which include protecting cells from oxidative damage and/or inhibiting production of ROS in a cell or subject, as well as preventing or reducing the extent of tissue damage caused by an ischemic event in a subject at elevated risk of such an event.