Shanghai Institutes for Biological Sciences Chinese Academy of Sciences
发明人:
Yufang Shi,Liming Du,Liangyu Lin,Ying Wang
申请号:
US15576091
公开号:
US20180200301A1
申请日:
2016.05.20
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a hypoxia-treated mesenchymal stem cell and the use thereof. The present invention discloses for the first time that treating mesenchymal stem cells with hypoxia can significantly promote alleviating or therapeutic effects of mesenchymal stem cells on inflammatory diseases. The present invention also discloses that the hypoxia-treated mesenchymal stem cell is capable of producing insulin-like growth factor-2, which plays a central role in the treatment of inflammatory diseases with the hypoxia-treated mesenchymal stem cell.