Soluble gp130 molecular variant useful as a medicine

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专利权人:

コナリス リサーチ インスティチュート アーゲー

发明人:

セーゲルト，ディルク,ヴェーツィッヒ，ゲオルク，ハー．,セーゲルト,ディルク,ヴェーツィッヒ,ゲオルク,ハー.

申请号：

JP2008546287

公开号：

JP5390191B2

申请日:

2006.12.22

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

A polypeptide-dimer built of two identical monomeric fragments comprising the domains 1 to 3 of the extracellular (soluble) part of glycoprotein (gp)130 and a certain polypeptide spacer are described, which are covalently linked with each other and which bear significant advantages concerning their production rate in host cells, their improved purification and their potential to bind to IL-6/soluble IL-6 receptor complexes. Furthermore, a pharmaceutical composition containing said dimeric molecule and various medical uses are described.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/