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Arilo hydrocarbon recipients and their antagonists
专利权人:
MAGENTA THERAPEUTICS; INC.
发明人:
GONCALVES, KEVIN A.,ROMERO, ARTHUR
申请号:
ARP180100921
公开号:
AR111375A1
申请日:
2018.04.12
申请国别(地区):
AR
年份:
2019
代理人:
摘要:
Dissemination refers to the antagonistic reactions of Ariel hydrocarbon recipients, such as substituted pyridine pyridine and pyridazole pyridine, and the expansion of blood stem cells through stem cell culture or blood-generated offspring in the presence of these mediators. S. In addition, by expanding the use of blood stem cells, patients can be treated for a variety of diseases. Dissemination also provides diagonal synthesis methods for tropospheric hydrocarbon receivers, such as substituted pyrazines and pyrazines.As well as a tool kit equipped with tropospheric oil receiver antagonists, it can be used to expand blood stem cells. Proposition 1: Compounds represented by formulas (1)L was selected from a group composed of -8311; - 7491 (Cr831222; - 7491; - R831222; - 749545; -).- O (Cr8322; 74911222; 74955); - 8345;- C(O) (CR831221); R831222; R74955;- C(s) (CR831221; R831222; 74955); - 8345;- S (o) 8320833183222 (Cr. 83212); 74191; R831222; 74955;- (Cr8322; 7491; R831222; 74955); - 8345;- No. 8311; No. 7491; (c) (o) (Cr831222); No. 7491; No. R831222; No. 749545;- No. 8311; No. 7491; (C(S) (Cr831222); No. 7491; No. R831222; No. 749545;- OC (O) (CR831221); R831222; R74955;- OC (S) (CR831221); R831222; R74955;- C(O) No. 8311; No. 7491 (Cr831222); No. 7491; No. R831222; No. 74955;- C(S) No. 8311; No. 7491 (Cr831222); No. 7491; No. R831222; No. 74955;- C(O)O(Cr8322); - 7491; - R831222; - 749545;...- C(s) o (cr8322; 7491; R831222; 749545);- S (O) 8322; No. 8311; No. 7491 (Cr. 831222); No. 7491; No. 831222; No. 74955;- No. 8311; No. 7491; No. 832222 (Cr. 8322); No. 7491; No. 831222; No. 74955;- 8311; 7491; C (O) 748311; 749595 (Cr83212); 7491; R831222; 74955; 8345; Y-N8311; 749112; C (O) or (Cr) 749112; R831222; 74955;R8311;7491;R8311; 74955;R83212, 749191 and R83212, 74955 and R83212, 74955 were independently selected from the group composed of hydrogen and asphalt replaced by C8321838324, with the independent number of each N being 2-6; R1 was selected from the group c
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