A pressure sensor for a medical injection system includes a cuff, a transducer embedded in the cuff, and a force transmitting member coupled to the transducer and exposed at an inner surface of the cuff, such that an outer surface of a tubing line of a fluid circuit of the system, when fitted within the cuff, contacts the force transmitting member. A limited length of the tubing line may have a greater compliance than a remainder of the line, in which case, the pressure sensor cuff fits around and encloses the limited length to provide support against plastic deformation, when pressures within the line are significantly greater than atmospheric. The pressure sensor may detect whether or not the cuff is properly fitted around the tubing line, and/or determine a characteristic of the tubing line.
