18/19F-labelled compounds which target the prostate specific membrane antigen

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专利权人:

The University of British Columbia;British Columbia Cancer Agency Branch

发明人:

Benard, Francois,Lin, Kuo-Shyan,Perrin, David,Liu, Zhibo,Kuo, Hsiou-Ting,Pan, Jinhe,Roxin, Aron,Lepage, Mathieu

申请号：

AU2017204979

公开号：

AU2017204979A1

申请日:

2017.01.10

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

This disclosure relates to novel compounds comprising a zwitterionic trifluoroborate prosthetic group which target prostate-specific membrane antigen (PSMA), e.g. in prostate cancer. The compounds have Formula I, wherein each Rl is an anionic group, L is a linker and R2BF3 is - N(R

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