Hydrophilic filtration during manufacture of vaccine adjuvants

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专利权人:

Novartis AG

发明人:

Kraus, Gottfried,Eskes, Robert

申请号：

AU2013202690

公开号：

AU2013202690A1

申请日:

2013.04.05

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2013202690A120130502.pdf#####ABSTRACT An improved method for the manufacture of an oil-in-water emulsion involves three procedures: (i) preparation of a preliminary emulsion (ii) microfluidization of the preliminary emulsion to reduce its droplet size and (iii) filtration of the microfluidized emulsion through a hydrophilic membrane. 5 The emulsions are useful as vaccine adjuvants.

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