Provided herein are synergistic herbicidal mixtures comprising a herbicidally effective amount of (a) penoxsulam and (b) pretilachlor. The compositions may also contain an agriculturally acceptable adjuvant or carrier. Provided herein are also methods of controlling the growth of undesirable vegetation in multiple crops including rice cereal and grain crops turf IVM sugar cane and tree and vine orchards and the use of this synergistic composition.