KORPHARM CO., LTD.;KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
发明人:
PARK, Gil Hong,SON, Geu Rim,HONG, Seong Su,CHOI, Chun Whan,CHOI, Yun Hyeok,KIM, Woo Jung,KIM, Han Kyeom,KANG, Jae Woo,LEE, Eun Jung,PARK, Serk In,LEE, Kee Ho,CHOI, Min Ji
申请号：
WO2017KR10822
公开号：
WO2018062895(A1)
申请日:
2017.09.28
申请国别(地区):
世界知识产权组织国际局
年份:
2018
代理人:
摘要：
The present invention relates to a composition comprising osmundacetone or a pharmaceutically acceptable salt thereof for preventing or treating bone diseases. More specifically, the present invention relates to: a composition comprising osmundacetone, a pharmaceutically acceptable salt thereof, or an osmunda japonica extract as an effective ingredient, for preventing or treating osteoporosis, rheumatoid arthritis, arthralgia, Paget disease, bone metastatic cancer, or fracture; a food composition for improvement; a use of a salt; and a treatment method. The composition according to the present invention shows a strong inhibitory activity against proliferation and differentiation of osteoclast which causes bone loss, and activation of differentiation of osteoblast, and thus can be usefully utilized in developing medicines for safe and effective treatment of bone diseases or functional foods for improving symptoms of bone diseases.
