The invention relates to aryl-sulphonamido compounds endowed with inhibitoryactivity against metallo proteases MMP, having Formula (I) below wherein R,R , R , R , R, R , n and mhave the meanings reported in the specification; the invention also refers tothe process for their preparation, to pharmaceutical compositions comprisingthem andto their use as therapeutic agents, particularly in the treatment ofdegenerativedisorders.