Naphthylurea derivatives and their medical applications

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专利权人:

テクノロジー;ファーマ;カンパニー、リミテッド;レイディアント;アンド

发明人:

フー、インチエン,ルオ、チーピン,チャン、イェンホン,ハン、リー,ワン、ユン,ルー、ホンフェイ

申请号：

JP2016544703

公开号：

JP6291066B2

申请日:

2014.08.20

申请国别(地区):

JP

年份:

2018

代理人:

摘要：

The present invention relates to naphthylurea derivatives. Such substances can significantly inhibit VEGFR2 and PDGFR-² receptor tyrosine kinase phosphorylation at nanomolar concentration levels. It is a novel type of tyrosine kinase inhibitors which can be used in the treatment of tyrosine kinase-mediated diseases or symptoms such as malignancies and ocular diseases accompanied with pathologic neovascularization.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/