Joseph M. DeSimone,Mathew Finniss,Mary Napier,Ashish Pandya,Matthew Parrott
申请号：
US14482624
公开号：
US20150065670A1
申请日:
2014.09.10
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Asymmetric bifunctional silyl (ABS) monomers comprising covalently linked pharmaceutical, chemical and biological agents are described. These agents can also be covalently bound via the silyl group to delivery vehicles for delivering the agents to desired targets or areas. Also described are delivery vehicles which contain ABS monomers comprising covalently linked agents and to vehicles that are covalently linked to the ABS monomers. The silyl modifications described herein can modify properties of the agents and vehicles, thereby providing desired solubility, stability, hydrophobicity and targeting.
