HAYNES, BARTON F.,LIAO, HUA-XIN,KORBER, BETTE T.,HRABER, PETER T.
申请号：
CA2983259
公开号：
CA2983259A1
申请日:
2016.04.19
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The invention provides HIV-1 immunogens, including envelopes (CH505) and selections therefrom, and methods for swarm immunizations using combinations of HIV-1 envelopes. Specifically, the invention provides compositions comprising at least one nucleic acid encoding HIV-1 envelope M11, M5, w020.14, w030.28, w078.15, w053.31 or any combination thereof or compositions comprising an HIV-1 envelope polypeptide M11, M5 w020.14, w030.28, w078.15, w053.31, or any combination thereof. Further provided are the nucleic acid sequences encoding HIV-1 envelopes and polypeptide sequences of HIV-1 envelopes.
